Bile duct injury outcomes following cholecystectomy: a cross sectional study

Am J Clin Exp Immunol. 2020 Jun 15;9(3):53-57. eCollection 2020.

Abstract

Background: Considering the importance of the repairing time in patients with biliary duct injury, the aim of this study was to evaluate the outcomes of patents with bile duct injury following cholecystectomy.

Methods: In this cross sectional study that was conducted on 64 patients with bile duct injury following cholecystectomy was referred to Shafa hospital in Tehran-Iran during 2010-2019 due to repair of biliary duct. Then patients were divided into two groups based on early and late referring time after bile duct injury, the postoperative outcomes were evaluated in two groups.

Results: The alanine transaminase (ALT) and the aspartate aminotransferase (AST) in the late group were significantly higher than the early group. There were significant differences between the two groups based on the results of endoscopic retrograde cholangiopancreatography (ERCP) and magnetic resonance cholangiopancreatography (MRCP) (P < 0.05). The frequency of bile duct dilatation, cholangitis and itching in late group were significantly higher than early group, also the frequency of uncomplicated outcome in the early group were significantly more than late group (P < 0.05).

Conclusion: The postoperative complication of biliary duct injury reduced, if patients diagnosed and referred at the same early stages (early referral).

Keywords: Bile duct injury; cholecystectomy; early; late; outcomes.